摘要:目的: 探討動脈硬化閉塞癥(ASO)和靜脈血栓形成(VT)患者同型半胱氨酸(Hcy)變化。 方法 :通過循環(huán)酶法對34例非動脈硬化閉塞癥(ASO)和靜脈血栓形成(VT)患者(對照組),30例動脈硬化閉塞癥(ASO)患者和26例靜脈血栓形成(VT)患者血液中Hcy進行測定。 結(jié)果 :循環(huán)酶法測定HCY的批內(nèi)平均變異系數(shù)為2．23％,批間平均變異系數(shù)為1．59％。34例對照組,〖WTBX〗t =1135,〖WTBX〗P =0266 gt;005;動脈硬化閉塞癥(ASO)組Hcy含量明顯高于對照組(〖WTBX〗P lt;O．05),靜脈血栓形成(VT)組Hcy含量高于對照組(〖WTBX〗P lt;0．O5)。 結(jié)論 :高同型半胱氨酸血癥可能是動脈硬化閉塞癥(ASO)和靜脈血栓形成(VT)及復(fù)發(fā)的致病因素?？蓪⑼桶腚装彼嶙鳛閯用}硬化閉塞癥(ASO)和靜脈血栓形成(VT)及復(fù)發(fā)的重要指標(biāo)。
Abstract: Objective: TO syudy the changes of the Homocysteine about Atherosclerosis obliterans and Venous thrombosis patients. Methods : To measure the Hcy in the blood of 34 healthy cases both non ASO and non VT(the comparison group),30 cases of ASO patients and 26 cases of VT patients respectively by enzymatic cycling assay。〖WTHZ〗Results :The average variation coefficient of Hcy within the groups was 223% and among the groups was 159% measured by enzymatic cycling assay.In the 34 cases of comparison group,t=1135,P=0266 gt;005,The content of Hcy in the blood of ASO patients group were significantly higher than the comparision group (P lt;005),and the content of Hcy in the blood of VT patients group were also higher than the comparison group (P lt;005). Conclusion : Hyper Hcy may be the pathogenic diathesis to form or to recrudesce ASO and VT.So we can treat Hcy as the significant index to form or to recrudesce ASO and VT.
引用本文： 趙慶海,沃秀芳,劉強. 動脈硬化閉塞癥和深靜脈血栓形成患者同型半胱氨酸臨床檢測結(jié)果及臨床意義. 華西醫(yī)學(xué), 2009, 24(10): 2577-. doi: 復(fù)制
版權(quán)信息： ?四川大學(xué)華西醫(yī)院華西期刊社《華西醫(yī)學(xué)》版權(quán)所有，未經(jīng)授權(quán)不得轉(zhuǎn)載、改編