闡述了 NNT 和 NNH 的定義和用途。NNT 用于治療前評估不治療給患者造成損害的可能性，NNH 用于評估治療可能給患者造成傷害的可能性，也可用于比較干預措施與陽性藥物比較的相對獲益或受損。與安慰劑比較時， NNT或NNH 為絕對效應量；與陽性藥物比較時，NNT 或 NNH 為相對效應量。當描述相對效應量時，通過RR或 OR、RD表示干預措施與對照的效應量大小關系。
引用本文： 吳泰相,劉關鍵. NNT和NNH的概念及應用. 中國循證醫(yī)學雜志, 2007, 07(9): 669-672. doi: 復制
版權信息： ?四川大學華西醫(yī)院華西期刊社《中國循證醫(yī)學雜志》版權所有，未經(jīng)授權不得轉(zhuǎn)載、改編
| 1. | Wu TX, Liu GJ, Zhang MM, et al. Systematic review of benefits and harms of artemisinin-type compounds fro preventing schistosomiasis. Natl Med J China, 2003, 83(14): 1219-1224. |
| 2. | Andreas L, David L, Sackett RS, et al. An assessment of clinically useful measures of the consequences of treatment. The New Eng J Med, 1988, 318(26): 1728-1733. |
| 3. | Fletcher RH, Fletcher SW, Wagner EH. Clinical Epidemiology. The Essentials. 3rd edition. Williams & Wilkins A Waverly Company. Baltimore, Maryland, USA. |
| 4. | Gordon Guyatt, Drummond Rennie. Users’ Guides to the medical literature. Essentials of Evidence-Based Cl inical Practice. JAMA ARCHIVES JORNALS. AMA Press. |
| 5. | Johansen HK, Gotzsche PC. Amphotericin B versus fluconazole for controlling fungal infections in neutropenic cancer patients. Cochrane Database of Systematic Reviews, Issue 2, 2002, (2): CD000239. |
| 6. | 吳泰相, 劉關鍵, 張鳴明, 等. 青蒿素類藥物預防日本血吸蟲感染效果及安全性的系統(tǒng)評價. 中華醫(yī)學雜志, 2003, 83(14): 1219-1224. |
- 1. Wu TX, Liu GJ, Zhang MM, et al. Systematic review of benefits and harms of artemisinin-type compounds fro preventing schistosomiasis. Natl Med J China, 2003, 83(14): 1219-1224.
- 2. Andreas L, David L, Sackett RS, et al. An assessment of clinically useful measures of the consequences of treatment. The New Eng J Med, 1988, 318(26): 1728-1733.
- 3. Fletcher RH, Fletcher SW, Wagner EH. Clinical Epidemiology. The Essentials. 3rd edition. Williams & Wilkins A Waverly Company. Baltimore, Maryland, USA.
- 4. Gordon Guyatt, Drummond Rennie. Users’ Guides to the medical literature. Essentials of Evidence-Based Cl inical Practice. JAMA ARCHIVES JORNALS. AMA Press.
- 5. Johansen HK, Gotzsche PC. Amphotericin B versus fluconazole for controlling fungal infections in neutropenic cancer patients. Cochrane Database of Systematic Reviews, Issue 2, 2002, (2): CD000239.
- 6. 吳泰相, 劉關鍵, 張鳴明, 等. 青蒿素類藥物預防日本血吸蟲感染效果及安全性的系統(tǒng)評價. 中華醫(yī)學雜志, 2003, 83(14): 1219-1224.