• 中國醫(yī)科大學(xué)附屬第一醫(yī)院 心臟外科,沈陽 110001;

目的 總結(jié)二尖瓣成形術(shù)治療二尖瓣反流患者的臨床經(jīng)驗(yàn),分析其療效。 方法 回顧性分析2007 年1 月至 2011 年 7月中國醫(yī)科大學(xué)附屬第一醫(yī)院采用二尖瓣成形術(shù)治療89 例二尖瓣中重度反流患者的臨床資料,其中男 51例,女 38 例;年齡21~64 (48.6±13.6)歲;病程1周~21 年。術(shù)前經(jīng)食管超聲心動(dòng)圖及術(shù)中探查發(fā)現(xiàn)二尖瓣中度反流(Ⅲ級(jí)) 40 例,重度反流 (Ⅳ級(jí)) 49 例。56例二尖瓣脫垂,脫垂病變累及A2區(qū)4例、A3區(qū)5例、P2區(qū)25例、P3區(qū)14例,累及多處8例;其中二尖瓣腱索斷裂37例,腱索冗長脫垂19例;瓣環(huán)擴(kuò)大42例。手術(shù)方式:前葉腱索轉(zhuǎn)移4 例 , 前葉人工腱索 6 例 ,前葉裂縫合2例,交界部縫合 6 例 ,后葉矩形切除加 Sliding (滑行) 技術(shù)43 例,后葉折疊縫合成形14例,后葉人工腱索12例,緣對(duì)緣成形 10 例和心包補(bǔ)片修補(bǔ)瓣葉穿孔 1 例,其中2種以上修復(fù)方式9例。全部患者均使用成形環(huán)加固瓣環(huán)。手術(shù)中應(yīng)用注水試驗(yàn)和食管超聲心動(dòng)圖檢查評(píng)價(jià)成形效果?!〗Y(jié)果 無圍術(shù)期死亡。術(shù)后心臟超聲心動(dòng)圖提示:二尖瓣無反流 (0 級(jí))15 例,微量反流 (Ⅰ級(jí))41 例,輕度反流 (Ⅱ級(jí)) 23 例,輕至中度反流 (Ⅲ級(jí))10 例。所有患者均無二尖瓣狹窄。術(shù)后隨訪77例(86.52%),隨訪時(shí)間3~58 (12.3±18.7) 個(gè)月。隨訪期間1例死于腦血管意外;1例行二尖瓣置換術(shù)?!〗Y(jié)論?綜合運(yùn)用多種二尖瓣成形技術(shù)治療二尖瓣中重度反流,可獲得良好的臨床療效。

引用本文: 修宗誼,谷天祥,喻磊,張敏,陳誠. 二尖瓣成形術(shù)治療二尖瓣反流89例臨床分析. 中國胸心血管外科臨床雜志, 2012, 19(6): 676-677. doi: 復(fù)制

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1.  Maisano F, Redaelli A, Pennati G, et al. The hemodynamic effects of double-orifice valve repair for mitral regurgitation:a 3D computational model. Eur J Cardiothorac Surg, 1999, 15 (4):419-425.
2.  Seeburger J, Borger MA, Doll N, et al. Comparison of outcomes of minimally invasive mitral valve surgery for posterior,anterior and bileaflet prolapse. Eur J Cardiothorac Surg, 2009, 36 (3):532-538.
3.  李京倖, 王靜, 杜瑩, 等. 二尖瓣后葉三角形切除的瓣膜成形術(shù)二例. 中國胸心血管外科臨床雜志, 2009, 16 (6):507..
4.  Suri RM, Schaff HV, Dearani JA, et al. Survival advantage and improved durability of mitral repair for leaflet prolapse subsets in the current era. Ann Thorac Surg, 2006, 82 (3):819-826.
5.  潘世偉, 胡盛壽, 胡曉鵬, 等. 國產(chǎn)瓣膜成形軟環(huán)在二尖瓣成形術(shù)中的應(yīng)用. 中國胸心血管外科臨床雜志, 2011, 18 (1):26-29..
6.  王鐵征, 徐方杰, 鄭悅, 等. 三種二尖瓣人工成形環(huán)的臨床效果. 中華胸心血管外科雜志, 2010, 26 (3):200-201..
7.  Chang BC, Youn YN, Ha JW, et al. Long-term clinical results of mitral valvuloplasty using flexible and rigid rings:a prospective and randomized study. J Thorac Cardiovasc Surg, 2007, 133 (4):995-1003.
8.  Hueb AC, Jatene FB, Moreira LF, et al. Ventricular remodeling and mitral valve modifications in dilated cardiomyopathy:new insights from anatomic study. J Thorac Cardiovasc Surg, 2002, 124 (6):1216-1224.
9.  Gorman JH 3rd, Gorman RC, Jackson BM, et al. Annuloplasty ring selection for chronic ischemic mitral regurgitation:lessons from the ovine model. Ann Thorac Surg, 2003, 76 (5):1556-1563.
10.  孫海寧, 王巍, 宋云虎, 等. 二尖瓣成形術(shù)治療二尖瓣前葉脫垂的療效分析. 中國胸心血管外科臨床雜志, 2010, 17 (4):283-286..
  1. 1.  Maisano F, Redaelli A, Pennati G, et al. The hemodynamic effects of double-orifice valve repair for mitral regurgitation:a 3D computational model. Eur J Cardiothorac Surg, 1999, 15 (4):419-425.
  2. 2.  Seeburger J, Borger MA, Doll N, et al. Comparison of outcomes of minimally invasive mitral valve surgery for posterior,anterior and bileaflet prolapse. Eur J Cardiothorac Surg, 2009, 36 (3):532-538.
  3. 3.  李京倖, 王靜, 杜瑩, 等. 二尖瓣后葉三角形切除的瓣膜成形術(shù)二例. 中國胸心血管外科臨床雜志, 2009, 16 (6):507..
  4. 4.  Suri RM, Schaff HV, Dearani JA, et al. Survival advantage and improved durability of mitral repair for leaflet prolapse subsets in the current era. Ann Thorac Surg, 2006, 82 (3):819-826.
  5. 5.  潘世偉, 胡盛壽, 胡曉鵬, 等. 國產(chǎn)瓣膜成形軟環(huán)在二尖瓣成形術(shù)中的應(yīng)用. 中國胸心血管外科臨床雜志, 2011, 18 (1):26-29..
  6. 6.  王鐵征, 徐方杰, 鄭悅, 等. 三種二尖瓣人工成形環(huán)的臨床效果. 中華胸心血管外科雜志, 2010, 26 (3):200-201..
  7. 7.  Chang BC, Youn YN, Ha JW, et al. Long-term clinical results of mitral valvuloplasty using flexible and rigid rings:a prospective and randomized study. J Thorac Cardiovasc Surg, 2007, 133 (4):995-1003.
  8. 8.  Hueb AC, Jatene FB, Moreira LF, et al. Ventricular remodeling and mitral valve modifications in dilated cardiomyopathy:new insights from anatomic study. J Thorac Cardiovasc Surg, 2002, 124 (6):1216-1224.
  9. 9.  Gorman JH 3rd, Gorman RC, Jackson BM, et al. Annuloplasty ring selection for chronic ischemic mitral regurgitation:lessons from the ovine model. Ann Thorac Surg, 2003, 76 (5):1556-1563.
  10. 10.  孫海寧, 王巍, 宋云虎, 等. 二尖瓣成形術(shù)治療二尖瓣前葉脫垂的療效分析. 中國胸心血管外科臨床雜志, 2010, 17 (4):283-286..