采用自制的簡(jiǎn)易狗自體肝移植模型，觀察肝動(dòng)脈缺血(HAI)對(duì)移植肝和膽管超微結(jié)構(gòu)的影響。結(jié)果發(fā)現(xiàn)：灌注后肝、膽細(xì)胞輕度水腫，線粒體基質(zhì)疏松，嵴較模糊；HAI3小時(shí)，肝、膽細(xì)胞水腫明顯加重，胞質(zhì)疏松，線粒體擴(kuò)大，嵴斷裂或消失，部分空泡變異出現(xiàn)絮狀電子致密斑，內(nèi)質(zhì)網(wǎng)明顯擴(kuò)張，核糖體解聚。表明HAI對(duì)供肝及膽管細(xì)胞有明顯損傷作用。提示肝臟移植后HAI是某些并發(fā)癥，特別是膽道并發(fā)癥的重要致病因素之一。
引用本文： 黎一鳴,楊文彬,紀(jì)宗正,康亞安. 肝動(dòng)脈缺血對(duì)犬自體移植肝和膽管超微結(jié)構(gòu)的影響. 中國(guó)普外基礎(chǔ)與臨床雜志, 1995, 2(4): 196-197Z轉(zhuǎn)封四. doi: 復(fù)制
版權(quán)信息： ?四川大學(xué)華西醫(yī)院華西期刊社《中國(guó)普外基礎(chǔ)與臨床雜志》版權(quán)所有，未經(jīng)授權(quán)不得轉(zhuǎn)載、改編
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- 4. Stevens LH, Bmond JC, Piper JB, et al. Hepaic artery thrombosis in Infants. Transplantation, 1992;53(2);396.
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