19只貓隨機(jī)分成A組和B組。A組7只接受全胰腺點(diǎn)狀注射酒精，B組12只經(jīng)主胰管插管注射酒精，并將導(dǎo)管留在主胰管內(nèi)造成主胰管部分梗阻，再全胰腺點(diǎn)狀注射酒精。結(jié)果：術(shù)后全部實(shí)驗(yàn)貓均發(fā)生急性壞死性胰腺炎（ANP）。A組2只貓（28.6%）在48小時(shí)內(nèi)死亡，5只貓術(shù)后6周胰腺組織形態(tài)和外分泌功能基本恢復(fù)正常。B組死亡4只（占33.3%），其中3只在術(shù)后48小時(shí)內(nèi)死亡，另1只在術(shù)后2周死亡。其余8只貓術(shù)后15周全部發(fā)展成慢性胰腺炎。由此提示單純胰腺壞死可在致病因去除后得到恢復(fù)；如果致病因繼續(xù)起作用，可造成組織學(xué)和功能方面的不可逆損害，最終可能發(fā)展成慢性胰腺炎。
引用本文： 趙華,屠建,鐘守先,唐偉松. 貓胰腺壞死后的轉(zhuǎn)歸初探. 中國(guó)普外基礎(chǔ)與臨床雜志, 1996, 3(1): 1-3. doi: 復(fù)制
| 1. | Ehrhardt-Schmelzer S,Otto J,Schlaeger R,et al.Fecal chymotrypsin for investigation of exocrine pancreatic function:a comparison of two newly developed tests with the titrimeteric method.Gastroenterol,1984;22:647. |
| 2. | Lankisch PG,Brauneis J,Otto J,et al.Pancreolauryl and NBT-PABA tests.Gastroenterol,1986;90:350. |
| 3. | Van De Kamer JH,Ten Bokkel Huinink H,Weyers HA.Rapid method for the determination of fat in the feces.J Biol Chem,1949;177:347. |
| 4. | Beger HG.Surgical management of necrotizing pancreatitis.Surg Clin North Am,1989;69:529. |
| 5. | Bradley EL Ⅲ,Allen K.A prospective longitudinal study of observation versus surgical intervention in the management of necrotizing pancreatitis.Am J Surg,1991;161:l0. |
| 6. | Warshaw AL.A guide to pancreatitis.Comp Ther,l980;6:49. |
| 7. | Fenton-Lee D,Imrie CW.Pancreatic necrosis:assessment of outcome related to quality of life and cost of management.Br J Surg,1993;80(12):1579. |
| 8. | Mitchell CJ,Playforth MJ,Mcmahon MJ.Functional recovery of the exocrine pancreas after acutepancreatitis.Scand J Gastroenterol,1983;18:5. |
| 9. | Sarles H.Proposal adopted unanimously by thepartocipants of the symposium on pancreatitis at marseilles.Gastroentecol,1965;7:7. |
| 10. | Klopple G,Maillet B.The morphological basis for the evolution of acute pancreatitis into chronic pancreatitis.Virchows Archiv A Pothol Anat,l992;420:1. |
- 1. Ehrhardt-Schmelzer S,Otto J,Schlaeger R,et al.Fecal chymotrypsin for investigation of exocrine pancreatic function:a comparison of two newly developed tests with the titrimeteric method.Gastroenterol,1984;22:647.
- 2. Lankisch PG,Brauneis J,Otto J,et al.Pancreolauryl and NBT-PABA tests.Gastroenterol,1986;90:350.
- 3. Van De Kamer JH,Ten Bokkel Huinink H,Weyers HA.Rapid method for the determination of fat in the feces.J Biol Chem,1949;177:347.
- 4. Beger HG.Surgical management of necrotizing pancreatitis.Surg Clin North Am,1989;69:529.
- 5. Bradley EL Ⅲ,Allen K.A prospective longitudinal study of observation versus surgical intervention in the management of necrotizing pancreatitis.Am J Surg,1991;161:l0.
- 6. Warshaw AL.A guide to pancreatitis.Comp Ther,l980;6:49.
- 7. Fenton-Lee D,Imrie CW.Pancreatic necrosis:assessment of outcome related to quality of life and cost of management.Br J Surg,1993;80(12):1579.
- 8. Mitchell CJ,Playforth MJ,Mcmahon MJ.Functional recovery of the exocrine pancreas after acutepancreatitis.Scand J Gastroenterol,1983;18:5.
- 9. Sarles H.Proposal adopted unanimously by thepartocipants of the symposium on pancreatitis at marseilles.Gastroentecol,1965;7:7.
- 10. Klopple G,Maillet B.The morphological basis for the evolution of acute pancreatitis into chronic pancreatitis.Virchows Archiv A Pothol Anat,l992;420:1.