• 四川大學(xué)華西醫(yī)院普外科(成都610041);

目的提高晚期膽囊癌的生存率及治療效果。方法對1990年1月至2001年6月我科手術(shù)治療的80例晚期膽囊癌患者的資料進(jìn)行回顧性分析,其中71例伴有阻塞性黃疸,15例捫及腹部包塊。對已浸潤周圍器官及膽管但尚無肝臟廣泛轉(zhuǎn)移或遠(yuǎn)處轉(zhuǎn)移的39例晚期膽囊癌進(jìn)行了擴(kuò)大根治術(shù)(其中11例合并胰十二指腸切除術(shù))。結(jié)果該39例術(shù)后存活8~37個月(平均存活18.1個月)。1、2、3年生存率分別為43.6%、20.5%及5.1%。對另41例已有肝臟轉(zhuǎn)移或腹膜種植轉(zhuǎn)移的晚期膽囊癌僅行姑息性手術(shù),術(shù)后隨訪除1例存活19個月外,其余均于1年內(nèi)死亡。結(jié)論對晚期膽囊癌的治療應(yīng)盡可能地行擴(kuò)大根治術(shù)。

引用本文: 周涌,吳言濤,嚴(yán)律南. 晚期膽囊癌的外科治療. 中國普外基礎(chǔ)與臨床雜志, 2002, 9(3): 189-190. doi: 復(fù)制

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  2. 2. Cubertafound P, Gainant A, Cuchiaro G, et al. Surgical treatment of 724 carcinomas of the gallbladder [J]. Ann Surg,1994; 219∶275.
  3. 3. 嚴(yán)律南. 膽囊癌與膽管癌診治進(jìn)展 [J]. 四川醫(yī)學(xué),1992; 13(1)∶34.
  4. 4. Shiral Y, Yoshida K, Tsukada F, et al. In apparent carcinoma of gallbladder [J]. Ann Surg, 1992; 215(6)∶326.
  5. 5. Nakamura S, Sakaguchi S, Suzuki S, et al. Aggressive surgery for carcinoma of the gallbladder [J]. Surgery, 1989; 106(6)∶467.
  6. 6. Matsumoto Y, Fujii H, Aoyama H, et al. Surgical treatment of primary carcinoma of the gallbladder based in the histologic analysis of 48 surgical speciments [J]. Am J Surg, 1991; 162(2)∶239.
  7. 7. 嚴(yán)律南. 晚期膽囊癌的手術(shù)治療 [J]. 中華外科雜志, 1997; 35(5)∶277.