目的 總結(jié)原發(fā)性腹膜后脂肪肉瘤(primary retroperitoneal liposarcoma,PRL)的臨床病理特征、診斷及治療方法。
方法 回顧性分析經(jīng)手術(shù)和活檢證實(shí)的23例PRL患者的臨床病理資料。
結(jié)果 首發(fā)癥狀及體征表現(xiàn)為腹部腫塊(91.3%,21/23),腹脹(56.5%,13/23)及腹痛(30.4%,7/23)。B超及CT的定位診斷準(zhǔn)確率分別為66.7%(12/18)和85.7%(12/14)。首次手術(shù)腫瘤完整切除16例(69.6%),其中8例聯(lián)合臟器切除; 部分切除3例(13.0%); 僅行活檢4例(17.4%)。PRL腫瘤完整切除術(shù)后復(fù)發(fā)率為75.0%(12/16),該12例中再次手術(shù)8例(66.7%)可完全切除腫瘤。
結(jié)論 CT是診斷PRL的重要手段,優(yōu)于B超; 手術(shù)以完整切除腫瘤為主,對(duì)侵犯臟器者采用累及臟器一并切除; 術(shù)后復(fù)發(fā)者可再次手術(shù)。
引用本文: 杜嘉林,吳澤宇,萬(wàn)進(jìn). 原發(fā)性腹膜后脂肪肉瘤23例報(bào)道. 中國(guó)普外基礎(chǔ)與臨床雜志, 2007, 14(6): 704-705. doi: 復(fù)制
版權(quán)信息: ?四川大學(xué)華西醫(yī)院華西期刊社《中國(guó)普外基礎(chǔ)與臨床雜志》版權(quán)所有,未經(jīng)授權(quán)不得轉(zhuǎn)載、改編
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- 2. 唐光健, 王儀生, 姜濤, 等. 腹膜后原發(fā)腫瘤的CT診斷 [J]. 中華放射學(xué)雜志, 1996; 30(4)∶229.
- 3. Neville A, Herts BR. CT characteristics of primary retroperitoneal neoplasms [J]. Crit Rev Comput Tomogr, 2004; 45(4)∶247.
- 4. Erzen D, Sencar M, Novak J. Retroperitoneal sarcoma: 25 ye-ars of experience with aggressive surgical treatment at the institute of oncology, Ljubljana [J]. J Surg Oncol, 2005; 91(1)∶1.
- 5. Alldinger I, Yang Q, Pilarsky C, et al. Retroperitoneal soft tissue sarcomas: prognosis and treatment of primary and recurrent disease in 117 patients [J]. Anticancer Res, 2006; 26(2B)∶1577.
- 6. 鄭樹(shù)森, 徐驍. 原發(fā)性腹膜后及腸系膜脂肪肉瘤的診斷及外科治療 [J]. 中國(guó)實(shí)用外科雜志, 2003; 23(9)∶540.
- 7. Singer S, Antonescu CR, Riedel E, et al. Histologic subtype and margin of resection predict pattern of recurrence and survival for retroperitoneal liposarcoma [J]. Ann Surg, 2003; 238(3)∶358.
- 8. Neuhaus SJ, Barry P, Clark MA, et al. Surgical management of primary and recurrent retroperitoneal liposarcoma [J]. Br J Surg, 2005; 92(2)∶246.
- 9. Malerba M, Doglietto GB, Pacelli F, et al. Primary retroperitoneal soft tissue sarcomas: results of aggressive surgical treatment [J]. World J Surg, 1999; 23(7)∶670.
- 10. Serio G, Tenchini P, Nifosi F, et al. Surgical strategy in primary retroperitoneal tumours [J]. Br J Surg, 1989; 76(4)∶385.