• 廣東省人民醫(yī)院普外三科(廣州510080);

目的  總結(jié)原發(fā)性腹膜后脂肪肉瘤(primary retroperitoneal liposarcoma,PRL)的臨床病理特征、診斷及治療方法。
方法  回顧性分析經(jīng)手術(shù)和活檢證實的23例PRL患者的臨床病理資料。
結(jié)果  首發(fā)癥狀及體征表現(xiàn)為腹部腫塊(91.3%,21/23),腹脹(56.5%,13/23)及腹痛(30.4%,7/23)。B超及CT的定位診斷準確率分別為66.7%(12/18)和85.7%(12/14)。首次手術(shù)腫瘤完整切除16例(69.6%),其中8例聯(lián)合臟器切除; 部分切除3例(13.0%); 僅行活檢4例(17.4%)。PRL腫瘤完整切除術(shù)后復發(fā)率為75.0%(12/16),該12例中再次手術(shù)8例(66.7%)可完全切除腫瘤。
結(jié)論  CT是診斷PRL的重要手段,優(yōu)于B超; 手術(shù)以完整切除腫瘤為主,對侵犯臟器者采用累及臟器一并切除; 術(shù)后復發(fā)者可再次手術(shù)。

引用本文: 杜嘉林,吳澤宇,萬進. 原發(fā)性腹膜后脂肪肉瘤23例報道. 中國普外基礎(chǔ)與臨床雜志, 2007, 14(6): 704-705. doi: 復制

1.  Dalton RR, Donohue JH, Mucha P, et al. Management of retroperitoneal sarcomas [J]. Surgery, 1989; 106(4)∶725.
2.  唐光健, 王儀生, 姜濤, 等. 腹膜后原發(fā)腫瘤的CT診斷 [J]. 中華放射學雜志, 1996; 30(4)∶229.
3.  Neville A, Herts BR. CT characteristics of primary retroperitoneal neoplasms [J]. Crit Rev Comput Tomogr, 2004; 45(4)∶247.
4.  Erzen D, Sencar M, Novak J. Retroperitoneal sarcoma: 25 ye-ars of experience with aggressive surgical treatment at the institute of oncology, Ljubljana [J]. J Surg Oncol, 2005; 91(1)∶1.
5.  Alldinger I, Yang Q, Pilarsky C, et al. Retroperitoneal soft tissue sarcomas: prognosis and treatment of primary and recurrent disease in 117 patients [J]. Anticancer Res, 2006; 26(2B)∶1577.
6.  鄭樹森, 徐驍. 原發(fā)性腹膜后及腸系膜脂肪肉瘤的診斷及外科治療 [J]. 中國實用外科雜志, 2003; 23(9)∶540.
7.  Singer S, Antonescu CR, Riedel E, et al. Histologic subtype and margin of resection predict pattern of recurrence and survival for retroperitoneal liposarcoma [J]. Ann Surg, 2003; 238(3)∶358.
8.  Neuhaus SJ, Barry P, Clark MA, et al. Surgical management of primary and recurrent retroperitoneal liposarcoma [J]. Br J Surg, 2005; 92(2)∶246.
9.  Malerba M, Doglietto GB, Pacelli F, et al. Primary retroperitoneal soft tissue sarcomas: results of aggressive surgical treatment [J]. World J Surg, 1999; 23(7)∶670.
10.  Serio G, Tenchini P, Nifosi F, et al. Surgical strategy in primary retroperitoneal tumours [J]. Br J Surg, 1989; 76(4)∶385.
  1. 1.  Dalton RR, Donohue JH, Mucha P, et al. Management of retroperitoneal sarcomas [J]. Surgery, 1989; 106(4)∶725.
  2. 2.  唐光健, 王儀生, 姜濤, 等. 腹膜后原發(fā)腫瘤的CT診斷 [J]. 中華放射學雜志, 1996; 30(4)∶229.
  3. 3.  Neville A, Herts BR. CT characteristics of primary retroperitoneal neoplasms [J]. Crit Rev Comput Tomogr, 2004; 45(4)∶247.
  4. 4.  Erzen D, Sencar M, Novak J. Retroperitoneal sarcoma: 25 ye-ars of experience with aggressive surgical treatment at the institute of oncology, Ljubljana [J]. J Surg Oncol, 2005; 91(1)∶1.
  5. 5.  Alldinger I, Yang Q, Pilarsky C, et al. Retroperitoneal soft tissue sarcomas: prognosis and treatment of primary and recurrent disease in 117 patients [J]. Anticancer Res, 2006; 26(2B)∶1577.
  6. 6.  鄭樹森, 徐驍. 原發(fā)性腹膜后及腸系膜脂肪肉瘤的診斷及外科治療 [J]. 中國實用外科雜志, 2003; 23(9)∶540.
  7. 7.  Singer S, Antonescu CR, Riedel E, et al. Histologic subtype and margin of resection predict pattern of recurrence and survival for retroperitoneal liposarcoma [J]. Ann Surg, 2003; 238(3)∶358.
  8. 8.  Neuhaus SJ, Barry P, Clark MA, et al. Surgical management of primary and recurrent retroperitoneal liposarcoma [J]. Br J Surg, 2005; 92(2)∶246.
  9. 9.  Malerba M, Doglietto GB, Pacelli F, et al. Primary retroperitoneal soft tissue sarcomas: results of aggressive surgical treatment [J]. World J Surg, 1999; 23(7)∶670.
  10. 10.  Serio G, Tenchini P, Nifosi F, et al. Surgical strategy in primary retroperitoneal tumours [J]. Br J Surg, 1989; 76(4)∶385.