• 中國醫(yī)學(xué)科學(xué)院 北京協(xié)和醫(yī)院外科（北京 100730）;

創(chuàng)傷、手術(shù)、感染、燒傷等極度應(yīng)激狀況下的危重患者常出現(xiàn)應(yīng)激性高血糖； 非糖尿病危重患者類似糖尿病的癥狀； 糖尿病危重患者則高血糖程度明顯加重。 創(chuàng)傷后出現(xiàn)不同水平的高血糖，隨著血糖的增高，其死亡危險性也呈階梯樣成倍增長［1，2］……

引用本文： 于健春. 控制血糖水平對外科危重患者預(yù)后的影響. 中國普外基礎(chǔ)與臨床雜志, 2009, 16(12): 956-957. doi: 復(fù)制

版權(quán)信息： ?四川大學(xué)華西醫(yī)院華西期刊社《中國普外基礎(chǔ)與臨床雜志》版權(quán)所有，未經(jīng)授權(quán)不得轉(zhuǎn)載、改編

1. Laird AM, Miller PR, Kilgo PD, et al. Relationship of early hyperglycemia to mortality in trauma patients [J]. J Trauma, 2004； 56(5): 1058-1062.
2. Srinivasan V， Spinella PC, Drott HR, et al. Association of timing, duration, and intensity of hyperglycemia with intensive care unit mortality in critically ill children [J]. Pediatr Crit Care Med, 2004； 5(4): 329-336.
3. Ramos M, Khalpey Z, Lipsitz S, et al. Relationship of perioperative hyperglycemia and postoperative infections in patients who undergo general and vascular surgery [J]. Ann Surg， 2008; 248(4): 585-591.
4. van den Berghe G, Wouters P, Weekers F, et al. Intensive insulin therapy in critically ill patients [J]. New Engl J Med, 2001； 345(19): 1359-1367.
5. Bellomo R. Does intensive insulin therapy protect renal function in critically ill patients? [J]. Nat Clin Pract Nephrol， 2008; 4(8):412-413.
6. Ray KK, Seshasai SR, Wijesuriya S, et al. Effect of intensive control of glucose on cardiovascular outcomes and death in patients with diabetes mellitus: a meta-analysis of randomized controlled trials [J]. Lancet， 2009; 373（9677）: 1765-1772.
7. Dellinger RP, Carlet JM， Masur H, et al. Surviving sepsis campaign guidelines for management of severe sepsis and septic shock [J]. Crit Care Med, 2004； 32(3): 858-873.
8. Dellinger RP, Levy MM, Carlet JM, et al. Surviving Sepsis Campaign: international guidelines for management of severe sepsis and septic shock: 2008 [J]. Crit Care Med， 2008; 36(1): 296-327.
9. NICE-SUGAR Study Investigators， Finfer S, Chittock DR, et al. Intensive versus conventional glucose control in critically ill patients [J]. N Engl J Med, 2009; 360(13): 1283-1297.
10. Charles Vega, Laurie Barclay. New guidelines address treatment of hospitalized patients with high blood glucose levels [J]. Endocr Pract, 2009; 15: 1-15. Diabetes Care. Published online May 8, 2009.
  1. 1. Laird AM, Miller PR, Kilgo PD, et al. Relationship of early hyperglycemia to mortality in trauma patients [J]. J Trauma, 2004； 56(5): 1058-1062.
  2. 2. Srinivasan V， Spinella PC, Drott HR, et al. Association of timing, duration, and intensity of hyperglycemia with intensive care unit mortality in critically ill children [J]. Pediatr Crit Care Med, 2004； 5(4): 329-336.
  3. 3. Ramos M, Khalpey Z, Lipsitz S, et al. Relationship of perioperative hyperglycemia and postoperative infections in patients who undergo general and vascular surgery [J]. Ann Surg， 2008; 248(4): 585-591.
  4. 4. van den Berghe G, Wouters P, Weekers F, et al. Intensive insulin therapy in critically ill patients [J]. New Engl J Med, 2001； 345(19): 1359-1367.
  5. 5. Bellomo R. Does intensive insulin therapy protect renal function in critically ill patients? [J]. Nat Clin Pract Nephrol， 2008; 4(8):412-413.
  6. 6. Ray KK, Seshasai SR, Wijesuriya S, et al. Effect of intensive control of glucose on cardiovascular outcomes and death in patients with diabetes mellitus: a meta-analysis of randomized controlled trials [J]. Lancet， 2009; 373（9677）: 1765-1772.
  7. 7. Dellinger RP, Carlet JM， Masur H, et al. Surviving sepsis campaign guidelines for management of severe sepsis and septic shock [J]. Crit Care Med, 2004； 32(3): 858-873.
  8. 8. Dellinger RP, Levy MM, Carlet JM, et al. Surviving Sepsis Campaign: international guidelines for management of severe sepsis and septic shock: 2008 [J]. Crit Care Med， 2008; 36(1): 296-327.
  9. 9. NICE-SUGAR Study Investigators， Finfer S, Chittock DR, et al. Intensive versus conventional glucose control in critically ill patients [J]. N Engl J Med, 2009; 360(13): 1283-1297.
  10. 10. Charles Vega, Laurie Barclay. New guidelines address treatment of hospitalized patients with high blood glucose levels [J]. Endocr Pract, 2009; 15: 1-15. Diabetes Care. Published online May 8, 2009.