目的 探討孤立性纖維性腫瘤的診斷及外科治療方法。
方法 回顧我院10年來經(jīng)手術切除并行病理檢查確診為孤立性纖維性腫瘤的病例資料,就其診斷和外科治療方法進行總結與分析。
結果 共16例次患者,腫瘤分別位于胸腔、腹股溝、后腹膜、外陰、頸部、下肢等部位,無明顯特異的臨床癥狀。所有病例均行手術完全切除腫瘤,術后經(jīng)病理學檢查和免疫組化染色檢查確診。對患者定期隨訪,其中2例分別于術后5年和7年腫瘤復發(fā),2例分別隨訪3年和5年后失訪,2例患者分別于隨訪的第9個月和16個月因全身多發(fā)轉移死亡,其余患者仍在隨訪中。
結論 孤立性纖維性腫瘤大多數(shù)病例表現(xiàn)為局部緩慢生長的無痛性腫塊,無明顯的臨床癥狀,術前診斷較困難,目前僅能依靠術后免疫組化檢查確診,手術切除是最佳的治療方法。
引用本文: 朱磊,林琳,郭大偉,孫文郁,王學范,梁健,姜曉峰. 孤立性纖維性腫瘤的診斷及外科治療. 中國普外基礎與臨床雜志, 2012, 19(1): 99-101. doi: 復制
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12. | Ota H, Kawai H, Yagi N, et al. Successful diagnosis diaphragmatic solitary fibrous tumor of the pleura by preoperative ultrasonography [J]. Gen Thorac Cardiovasc Surg, 2010, 58(9):485-487. |
13. | Insabato L, Siano M, Somma A, et al. Extrapleural solitary fibrous tumor: a clinicopathologic study of 19 cases [J]. Int J Surg Pathol, 2009, 17(3): 250-254. |
14. | Tam ES, Chen EC, Nijhawan N, et al. Solitary fibrous tumor of the orbit: a case series [J]. Orbit, 2008, 27(6): 426-431. |
15. | Takizawa I, Saito T, Kitamura Y, et al. Primary solitary fibrous tumor (SFT) in the retroperitoneum [J] . Urol Oncol,2008,26(3): 254-259. |
16. | Ito H, Fukuda M, Imamura Y, et al. A malignant solitary fibrous tumor in the retroperitoneum [J] . Int J Clin Oncol, 2008,13(2): 173-175. |
17. | Cranshaw IM, Gikas PD, Fisher C, et al. Clinical outcomes of extra-thoracic solitary fibrous tumors [J]. Eur J Surg Oncol,2009, 35(9): 994-998. |
- 1. Insabato L, Siano M, Somma A, et al. Extrapleural solitary fibrous tumor: a clinicopathologic study of 19 cases [J]. In J Surg Pathol, 2009, 17(3): 250-254.
- 2. Suehisa H, Yamashita M, Komori E, et al. Solitary fibrous tumor of the mediastinum [J] . Gen Thorac Cardiovasc Surg,2010, 58(4): 205-208.
- 3. 陳卉嬌, 張紅英, 李響, 等. 26 例孤立性纖維性腫瘤臨床病理及免疫組化特征 [J] . 四川大學學報( 醫(yī)學版), 2004, 35(5):675-679.
- 4. Cox DP, Daniels T, Jordan RC. Solitary fibrous tumor of the head and neck [J]. Oral Surg Oral Med Oral Pathol Oral Radiol Endod, 2010, 110(1) : 79-84.
- 5. Yilmaz C, Kabatas S, Ozen OL, et al. Solitary fibrous tumor [J]. J Clin Neurosci, 2009, 16(12): 1578-1581.
- 6. Tanaka M, Sawai H, Okada Y, et al. Malignant solitary fibrous tumor originating from the peritoneum and review of the literature [J] . Med Sci Monit, 2006, 12(10): CS95- CS98.
- 7. Bishop JA, Rekhtman N, Chun J, et al. Malignant solitary fibrous tumor: cytopathologic findings and differential diagnosis [J] . Cancer Cytopathol, 2010, 118(2): 83-89.
- 8. Ambrosini-Spaltro A, Eusebi V. Meningeal hemangiopericytomas and hemangiopericytoma/solitary fibrous tumors of exrtracranial soft tissues: a comparison [J] . Virchows Arch, 2010,456(4): 343-354.
- 9. Mosquera JM, Fletcher CD. Expanding the spectrum of malignant progression in solitary fibrous tumors: a study of 8 cases with a discrete anaplastic component— is this dedifferentiated SFT [J] . Am J Surg Pathol, 2009, 33(9): 1314-1321.
- 10. Bini A, Brandolini J, Davoli F, et al. Solitary fibrous tumor of the pleura: surgery and clinical course in 18 cases [J]. Asian Cardiovasc Thorac Ann, 2009, 17(4): 378-381.
- 11. Pak PS, Yanagawa J, Abtin F, et al. Surgical management of endobronchial solitary fibrous tumors [J]. Ann Thorac Surag,2010, 90(2): 659-661.
- 12. Ota H, Kawai H, Yagi N, et al. Successful diagnosis diaphragmatic solitary fibrous tumor of the pleura by preoperative ultrasonography [J]. Gen Thorac Cardiovasc Surg, 2010, 58(9):485-487.
- 13. Insabato L, Siano M, Somma A, et al. Extrapleural solitary fibrous tumor: a clinicopathologic study of 19 cases [J]. Int J Surg Pathol, 2009, 17(3): 250-254.
- 14. Tam ES, Chen EC, Nijhawan N, et al. Solitary fibrous tumor of the orbit: a case series [J]. Orbit, 2008, 27(6): 426-431.
- 15. Takizawa I, Saito T, Kitamura Y, et al. Primary solitary fibrous tumor (SFT) in the retroperitoneum [J] . Urol Oncol,2008,26(3): 254-259.
- 16. Ito H, Fukuda M, Imamura Y, et al. A malignant solitary fibrous tumor in the retroperitoneum [J] . Int J Clin Oncol, 2008,13(2): 173-175.
- 17. Cranshaw IM, Gikas PD, Fisher C, et al. Clinical outcomes of extra-thoracic solitary fibrous tumors [J]. Eur J Surg Oncol,2009, 35(9): 994-998.