• 四川大學(xué)華西醫(yī)院 1腎內(nèi)科;2皮膚科,四川成都 610041;

目的:探討銀屑病合并蛋白尿患者的臨床特點(diǎn)。方法:回顧性分析1996年1月~2005年8月收治的銀屑病合并蛋白尿者臨床資料,并與銀屑病非蛋白尿者的臨床特點(diǎn)比較。結(jié)果:銀屑病合并不明原因蛋白尿48例,皮膚受累面積與蛋白尿程度無(wú)相關(guān)關(guān)系(P>0.05),但銀屑病合并蛋白尿組的銀屑病病程更短,腎臟病理熒光表現(xiàn)為IgA沉積為主。蛋白尿組皮膚受累面積與非蛋白尿組皮膚受累面積比較,無(wú)統(tǒng)計(jì)學(xué)意義(P>0.05),蛋白尿組和非蛋白尿組的病程也無(wú)統(tǒng)計(jì)學(xué)差異(P>0.05)。結(jié)論:銀屑病合并不明原因蛋白尿值得重視,有必要對(duì)其發(fā)病機(jī)制、臨床特點(diǎn)、病理特征進(jìn)行深入的研究。

引用本文: 鐘慧,馬愛(ài)景,蔣獻(xiàn). 銀屑病合并蛋白尿48例臨床分析. 華西醫(yī)學(xué), 2008, 23(1): 117-118. doi: 復(fù)制

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2. Madeddu P,Ena P,Glorioso N,et al.High prevalence of microproteinuria,an early index of renal impairment,in patients withdiffuse psoriasis[J].Nephron,1988,48(3):222-225..
3. Alenius GM,Stegmayr BG,Dahlqvist SR.Renalabnormalities in a population of patients with psoriatic arthritis[J].Scand JRheumatol,2001,30(5):271-4..
4. Szepietowski JC,Bielicka E,Wasik F,et al.Microalbuminuria as a subclinical marker of renal in subjects with psoriasis vulgaris[J].J Eur Acad Dermatol Venereol,2000,14(6):513-514..
5. Yamamoto M,Yorioka T,et al.A Case of IgA nephropathy associated with psoriasis vulgaris[J].Nippon Jinzo Gakkai Shi,1994,36(6):779-783..
6. Tejinder S,Marjorie F,John J,et al.IgA nephropathy in psoriasis[J].Am J Nephrol,1998,18:425-429..
7. 陳惠萍,王文榮,等.銀屑病所致的腎損害[J].腎臟病與透析移植雜志,2003,12(4):393-396..
8. Yamaji H,Shikata K,Wada J,et al.A case of membranous nephropathy associated with psoriasis vulgaris[J].Acta Derm Venereol,1996,76(6):492..
9. Kida H,Asamoto T,Abe T,et al.Psoriasis vulgaris associated with mesangiocapillary glomerulonephritis[J].Clin Nephrol,1985,23(50):255-257..
10. Saxena S,Verma K,Bhuyan UN,et al.Amyloidosis complicating psoriatic arthropathy[J].J Assoc Physicians India,1992,40(9):609-610..
11. Hall RP,Peck GL,Lawley TJ.Circulating IgA immune complexes in patients with psoriasis[J].J Invest Dermatol,1983,80(6):465-468..
12. 楊劍輝,井艷華,張紀(jì)蕓.銀屑病患者腎臟損害的臨床與病理觀察[J].中華皮膚科雜志,2002,35(2):155..
13. 于厚南,梅長(zhǎng)林,廖萬(wàn)清.銀屑病并發(fā)慢性腎功能衰竭8例報(bào)道[J].腎臟病與透析腎移植雜志,1997,6(3):242-243..
  1. 1. [1]Omdal R,Husby G.Renal affection in patients with ankylosing sponylitis and psoriatic arthritis[J].Clin Rheumatol,1987,6(1):74-79..
  2. 2. Madeddu P,Ena P,Glorioso N,et al.High prevalence of microproteinuria,an early index of renal impairment,in patients withdiffuse psoriasis[J].Nephron,1988,48(3):222-225..
  3. 3. Alenius GM,Stegmayr BG,Dahlqvist SR.Renalabnormalities in a population of patients with psoriatic arthritis[J].Scand JRheumatol,2001,30(5):271-4..
  4. 4. Szepietowski JC,Bielicka E,Wasik F,et al.Microalbuminuria as a subclinical marker of renal in subjects with psoriasis vulgaris[J].J Eur Acad Dermatol Venereol,2000,14(6):513-514..
  5. 5. Yamamoto M,Yorioka T,et al.A Case of IgA nephropathy associated with psoriasis vulgaris[J].Nippon Jinzo Gakkai Shi,1994,36(6):779-783..
  6. 6. Tejinder S,Marjorie F,John J,et al.IgA nephropathy in psoriasis[J].Am J Nephrol,1998,18:425-429..
  7. 7. 陳惠萍,王文榮,等.銀屑病所致的腎損害[J].腎臟病與透析移植雜志,2003,12(4):393-396..
  8. 8. Yamaji H,Shikata K,Wada J,et al.A case of membranous nephropathy associated with psoriasis vulgaris[J].Acta Derm Venereol,1996,76(6):492..
  9. 9. Kida H,Asamoto T,Abe T,et al.Psoriasis vulgaris associated with mesangiocapillary glomerulonephritis[J].Clin Nephrol,1985,23(50):255-257..
  10. 10. Saxena S,Verma K,Bhuyan UN,et al.Amyloidosis complicating psoriatic arthropathy[J].J Assoc Physicians India,1992,40(9):609-610..
  11. 11. Hall RP,Peck GL,Lawley TJ.Circulating IgA immune complexes in patients with psoriasis[J].J Invest Dermatol,1983,80(6):465-468..
  12. 12. 楊劍輝,井艷華,張紀(jì)蕓.銀屑病患者腎臟損害的臨床與病理觀察[J].中華皮膚科雜志,2002,35(2):155..
  13. 13. 于厚南,梅長(zhǎng)林,廖萬(wàn)清.銀屑病并發(fā)慢性腎功能衰竭8例報(bào)道[J].腎臟病與透析腎移植雜志,1997,6(3):242-243..